HAEMATOLOGICAL AND BIOCHEMICAL EFFECTS OF HALOFANTRINE HYDROCHLORIDE (HALFAN) ON FEMALE ALBINO RATS
ALAEBO, P. O.,ONUOHA, U. N., EBHOHON, O.,ONYEABO, C.,ENYA, E. AND UGWU, P.
ABSTRACT
Malaria has remained a major killer disease in the tropics and its treatment has been greatly hindered by increased drug resistance. This study evaluated hematological and biochemical effect of doses of Halofantrine hydrochloride (HALFAN) a phenanthrene methanol drug used for the therapeutic treatment of malaria on female albino rats. Twenty (20) female albino rats divided into four (4) groups (A-D) of five (5) rats each were used. Group A (control) received 0.1 mg/kg body weight of normal saline, while…