BIUJBAS 8(1) 1
ASSESSMENT OF THE PARASITOLOGICAL QUALITY OF ROOF-COLLECTED RAINWATER STORED IN CISTERNS FOR DOMESTIC USE IN THE SUBURBS OF BENIN CITY, SOUTHERN NIGERIA
WOGU, M. D. AND USIWO, P. E.
ABSTRACT
One hundred and twenty (120) roof-collected rainwater samples in six domestic cistern sites in the suburbs of Benin City, southern Nigeria, were investigated in a cross-sectional survey to determine the parasitological quality. Seventeen (14.2%) rainwater samples analysed were contaminated with parasites and exceeded the acceptable limit of the WHO for safe drinking water. Site environment had a significant effect on the parasitological….
BIUJBAS 8(1)2
HAEMATOLOGICAL AND BIOCHEMICAL EFFECTS OF HALOFANTRINE HYDROCHLORIDE (HALFAN) ON FEMALE ALBINO RATS
ALAEBO, P. O.,ONUOHA, U. N., EBHOHON, O.,ONYEABO, C.,ENYA, E. AND UGWU, P.
ABSTRACT
Malaria has remained a major killer disease in the tropics and its treatment has been greatly hindered by increased drug resistance. This study evaluated hematological and biochemical effect of doses of Halofantrine hydrochloride (HALFAN) a phenanthrene methanol drug used for the therapeutic treatment of malaria on female albino rats. Twenty (20) female albino rats divided into four (4) groups (A-D) of five (5) rats each were used. Group A (control) received 0.1 mg/kg body weight of normal saline, while…
BIUJBAS 8(1)3
ISOLATION AND MOLECULAR CHARACTERIZATION OF Xanthomonas campestris FROM TOMATOES PLANT (SEED) IN WESTERN DELTA REGION OF DELTA STATE
EWEKA, D. A., IGERE, B. E., OKOLIE, E. C., EBHONU, P. J. AND OKINEDO, J. I.
ABSTRACT
Tomatoes plant and seeds have been affected by bacterial contamination and early infection, during its developmtal stage resulting plant disease cases in affected farm-lands of Delta State. Our study investigates isolation and molecular characterisation of Xanthomonas campestris from tomatoes plant in Oghara. Four locations in the study area were surveyed while freshly harvested tomato and suspected bacterial leaf spot infected tomato plant samples were collected and analyzed. Standard microbiological techniques for the isolation of bacteria were employed. Morphological and biochemical characteristics, viz., Gram’s reaction…
BIUJBAS 8(1)4
CHANGES IN PHYSICOCHEMICAL AND HEAVY METAL PROPERTIES OF SOIL TREATED WITH SPENT ENGINE OIL AND POULTRY MANURE AFTER 12 WEEKS OF GROWING Phyllanthus urinaria
IFEDIORA, N. H., OTI, V. O. AND ADAJI, A.
ABSTRACT
Lubricating oil usually contains chemical additives including amines, phenols, benzenes,
calcium, zinc, barium, magnesium, phosphorus, sulphur and lead. This study was done to
assess the changes in physicochemical and heavy metal properties of soil treated with spent
engine oil and poultry manure after 12 weeks of growing Phyllanthus urinaria. It was done
in the screen house of the Department of Plant Science and Biotechnology, Michael Okpara
university of Agriculture, Umudike (MOUAU). Soil samples at the depth of 0 – 15 cm, spent
engine oil and…
BIUJBAS 8(1)5
THERAPEUTIC DRUG MONITORING STUDY ON COFORMULATED 600-MG EFAVIRENZ, 300-MG TENOFOVIR DISOPROXIL FUMARATE AND 300-MG LAMIVUDINE AMONG HIV-POSITIVE PATIENTS WITH IMMUNE SUPPRESSION
OSHIM, I. O., ERHUNMWUNSE, R. U., OBI, C. M., ODEYEMI, O. AND OKWELOGU, I. S.
ABSTRACT
Background: Combination of three antiviral drugs are used to treat adult and adolescent HIV
infection. These antiretroviral drugs stop an enzyme (reverse transcriptase) that HIV uses to
replicate itself. By doing this, they stop the infection from spreading. Objectives: the study is
aimed at evaluating therapeutic drug monitoring on co-formulated 600-mg efavirenz, 300-mg
tenofovir disoproxil fumarate and 300-mg lamivudine among HIV-positive patients. Methods: A
Retrospective….
BIUJBAS 8(1)6
A MODIFIED PREDICTION ERROR SUM OF SQUARES CRITERION FOR BANDWIDTH SELECTION IN LOCAL QUADRATIC REGRESSION
EDIONWE, E. AND OSEMWENKHA, S. O.
ABSTRACT
Bandwidth (smoothing parameter) is considered the most crucial parameter in the application of nonparametric regression model. For the purpose of selecting adaptive bandwidths for the Local Quadratic Regression (LQR) in the response surface settings, we present a modified Prediction Error Sum of Square (PRESS) criterion using a penalty term derived from the sum of the range of kernel weights at each of the data points. LQR is applied to a multiple response problem from the literature using the current PRESS criterion and the proposed version for optimal bandwidth selection. The proposed…
BIUJBAS 8(1)7
MOLECULAR DETECTION OF SOME DRUG RESISTANT AND VIRULENCE GENES OF METHICILLIN RESISTANT Staphylococcus aureus FROM HOSPITALS IN ABIA STATE, NIGERIA
FEDIORA, A. C., NWABUEZE, R. N., AMADI, E. S.AND CHIKWENDU, C. I.
ABSTRACT
Methicillin resistant Staphylococcus aureus (MRSA) is a major pathogen implicated in healthcare and community associated infections. This study was aimed at determining the antimicrobial resistance pattern and genotypic characteristics of some clinical MRSA isolates from federal medical centre Umuahia and Abia State teaching hospital Aba both in Abia State, Nigeria with respect to resistance and virulence genes. A total of 40 MRSA isolates identified using cefoxitin discs were obtained from…
BIUJBAS 8(1)8
IMPROVING THE PERFORMANCE OF SEMIPARAMETRIC MODEL ROBUST REGRESSION 2 VIA THE INCLUSION OF THESTATISTICALLY SIGNIFICANT
INTERACTION TERMS IN THE MODEL MATRIX
*EDIONWE, E.1 AND OSEMWENKHA, S. O.
ABSTRACT
Response Surface Methodology (RSM) comes handy when a researcher wants to determine the value of each of the explanatory variables that simultaneously optimize the response variables. In the modelling phase of RSM, a suitable regression model is fitted the data generated from the experimental design phase. The fitted model is subsequently subjected to an appropriate optimization routine in order to obtain the optimal solution of the study. Currently….
BIUJBAS 8(1)9
TUDIES ON THE CO-INFECTION OF HIV AND ATYPICAL MYCOBACTERIA IN MERCY SPECIALIST HOSPITAL AHIAEKE-NDUME, ABIA STATE, NIGERIA
NWANKWO, I. U., EDWARD, K. C. AND UDENSI, G. C.
ABSTRACT
Tuberculosis (TB) and HIV/AIDS are major public health issues globally and the burden of these diseases is particularly significant in Nigeria. This study therefore determined the prevalence and distribution of co-infection of HIV and atypical mycobacteria among individuals in Mercy Specialist Hospital Ahiaeke-Ndume, Abia State, Nigeria. A total of the 115 individuals were enrolled into the study, 43.5% (50) males and 56.5% (65) females. The serum was screened…
BIUJBAS 8(1)10
ASSESSING COVID-19 KNOWLEDGE, PREVENTION PRACTICES, AND ENVIRONMENTAL IMPACT AWARENESS AMONG HEALTHCARE PROFESSIONALS AT WARRI CENTRAL HOSPITAL, DELTA STATE
OSIAN, E.A., ODJIGHORO, J., OLAWALE, Y. A., AND ONAIWU, E.G.4
ABSTRACT
This study examines healthcare professionals’ understanding of COVID-19 at Central Hospital, Warri, Delta State, with a focus on its causes, preventive measures, and environmental impacts. Using the Health Belief Model (HBM), a survey research design involving 200 healthcare workers reveals high COVID-19 knowledge (96.4%) and positive perceptions (85.5%) and attitudes (86.5%) towards its environmental impacts. Many respondents (78.1%) report noticeable environmental changes…
BIUJBAS 8(1)11
REVIEW ON NATURAL DRUG FORMULATION FROM ONION, UNRIPE LEMON, AND GARLIC: AN INTERDISPLINARY APPROACH
ONAIWU, E. G. AND ELUSOJI, C. I.
ABSTRACT
Natural drug formulations derived from botanical sources have garnered increasing attention for their potential health benefits and reduced environmental impact. This manuscript provides a comprehensive review of a ground-breaking collaboration between environmental chemists and medical practitioners (i.e., nursing, pharmacy, medical biochemistry etc.) in the development of a natural drug formulation utilizing
onion, unripe lemon, and garlic. The collaborative effort emphasizes the need to balance medical efficacy with environmental sustainability. We explore the formulation’s efficacy,